Asunto(s)
Portador Sano/diagnóstico , Farmacorresistencia Bacteriana Múltiple , Enterobacteriaceae/aislamiento & purificación , Heces/microbiología , Tamizaje Masivo , beta-Lactamasas , Portador Sano/epidemiología , Portador Sano/microbiología , Preescolar , Farmacorresistencia Bacteriana Múltiple/genética , Enterobacteriaceae/genética , Enterobacteriaceae/metabolismo , Infecciones por Enterobacteriaceae/diagnóstico , Infecciones por Enterobacteriaceae/epidemiología , Infecciones por Enterobacteriaceae/microbiología , Femenino , Tracto Gastrointestinal/microbiología , Humanos , Lactante , Recién Nacido , Masculino , Tamizaje Masivo/métodos , Togo/epidemiología , beta-Lactamasas/genética , beta-Lactamasas/metabolismoRESUMEN
PURPOSE: HIV rapid diagnostic tests (RDT) could be greatly contributive for a universal access to HIV diagnosis. However, according to the WHO, these tests need to be assessed before they can be used in routine. METHOD AND RESULTS: We assessed 9 RDT in routine clinical use between 2009 and 2013. The sensitivity and specificity observed for 7 tests were≥99% and≥98%, respectively: FIRST RESPONSE HIV1-2-O PMC Medical, India, GENIE Fast HIV 1-2 and GENIE™ III HIV(1/2) Bio-Rad, France, HIV TRI-DOT+Ag;J. Mitra, INDIA; SD BIOLINE HIV(1/2) 3.0 and SD BIOLINE HIV/SYPHILIS DUO Standard Diagnostic, Korea; and VIKIA HIV(1/2); BioMérieux, France. Two tests had performances inferior to WHO recommendations: INSTI HIV1/2 Biolytical Canada; sensitivity=97.8% and HEXAGON HIV HUMAN GmbH Germany; specificity=94.8%. CONCLUSION: Seven of 9 RDT had excellent performances. Nevertheless, they can be used only after training staff, and taking into account national algorithm for their safe use.
